Zachary Quinto's medical drama Brilliant Minds just lost several original cast members. During the midseason return on Monday, January 5, Dr. Jacob Nash (Spence More II) and Dr. Van Markus (Alex MacNicoll) left the hospital. Jacob chose to depart after being offered a spot in his residency program in Texas. "When I got injured, doctors were in and out of the room, telling me what was best for me. No one ever took the time to get to know me. Not the way you take the time to get to know your patients," he told Quinto's character Wolf.