Haseen Dillruba stars Taapsee Pannu as Rani Kashyap, a woman whose husband Rishabh, played by Vikrant Massey, is found dead under suspicious circumstances. The police discover a charred body in their house, which is identified as Rishabh's through a severed hand. As the investigation progresses, Rani becomes the prime suspect. The narrative moves between the present-day police questioning and flashbacks that explore Rani and Rishabh's marriage.