Rob Reiner's relationship with his wife, Michele Singer Reiner, helped inspire the beloved ending of When Harry Met Sally. "You want to hear something interesting about that? The original ending of the film we had was that Harry and Sally didn't get together because I had been married for 10 years," Rob previously shared in a February 2024 episode of Who's Talking to Chris Wallace on HBO Max. "I had been single for 10 years, and I couldn't figure out how I was ever going to be with anybody. That gave birth to When Harry Met Sally.