Article continues below advertisementRob Reiner and Michele Reiner's relationship sparked on the set of one of his most iconic films, blossoming into a decades-long love story before tragically ending in murder, allegedly at the hands of their own son.Article continues below advertisementHow Did Rob Reiner and Michelle Reiner Meet? Source: MEGARob and Michele Reiner met on the set of 'When Harry Met Sally...'Rob and Michele met on the set of the late '80s filmWhen Harry Met Sally..., where she was a photographer and he was the film's director.