Pauline Potter, Lisa Fleming, Gina Krasley, Robert Buchel and more former My 600-Lb. Life stars have tragically died over the years. My 600-Lb. Life premiered on TLC in 2012. While season 1 featured patients who were filmed over a period of seven years, the show tweaked its format and documented cast members for one year starting in season 2. By season 8, some stars were only filmed for six months. Tragedy struck the reality show for the first time in 2013 when season 1 star Henry Foots died. Five years later, Lexington County Coroner's Office in South Carolina confirmed to Us Weekly that James "L.B." Bonner died by suicide. "On the show, viewers saw L.B. struggle with obesity following a tragic accident that claimed his right leg. Even though he once weighed 650 pounds, L.B.'s hard work and dedication helped get him in the 200-pound range," the network said in a statement in August 2018 following his untimely death. "His spirit and determination as displayed through his story, quickly made L.B. a fan favorite, and family and friends have taken to L.B.'s Facebook page to commemorate his life. TLC was deeply saddened to hear of L.B.'s passing and is honored to have shared his honest and courageous story on My 600-lb Life." That same month, fellow season 6 star Fleming died at the age of 50, with her daughter, Danielle, telling TMZ that "she was sick and her body was tired and her body just gave out." In 2025, season 3 participant Potter and season 11's Latonya Pottain both died. They were 62 and 40, respectively. Scroll through for more My 600-Lb. Life tragedies: