Nikki Reed has reflected on a long-term medical issue - and how she eventually found answers. "The placebo effect is real, but it doesn't work on me," Reed, 37, said on the Wednesday, November 12, episode of "The Squeeze" podcast. "I had spent so much time exploring a lot of this and the world of wellness and supplements. I won't bore you with it, but I ended up in this crazy health scare that spanned years and years." Reed subsequently sought advice from multiple physicians. "I was seeing, as you can imagine, great doctors because I'm an information seeker," she recalled. "I'm seeking out the best doctors that I can and really researching for years and years. I couldn't figure this out and it was making me crazy, but what was making me equally as crazy was the amount of things I was being sold that weren't working." Nikki Reed's 19-Hour Day on the Farm: Inside Her Life With Ian Somerhalder Without disclosing her diagnosis, Reed revealed that she had been prescribed a number of medications that didn't work. "Not only do they not work, but it's an industry that's capitalizing on people's hope because they're hoping that it works," she claimed on Wednesday. "They're taking these things, and they're spending their hard-earned money on this massive belief that they're going to get better from an industry that's taking advantage of them." Reed's personal experience soon "lit a fire" for her to create products that consumers "can feel in the moment" work. (Reed launched her wellness brand, The Absorption Company, in 2024 with her husband, Ian Somerhalder.) "I live in this space because I love the world of nontraditional medicine, but I also love Western [medicine] that's very cut and dry," she said. "I think there's a place for all of it, and I live somewhere in the middle of this space of wellness but also traditional medicine. I see and appreciate both." Nikki Reed Reveals If the Door to Her Acting Career Is 'Closed' for Good Reed previously revealed that her health scare began after she welcomed daughter Bodhi in 2017. "Shortly after I had my first child, when she was about 2 and a half years old, I kind of entered into this bizarre mystery health crisis," Reed, who shares two kids with Somerhalder, said on a July episode of "The Art of Being Well" podcast. "Every blood test in the world, every doctor in the world, [or at least] that's what it felt like. I know I'm speaking in extremes, [but I] was going down every single path to figure this out. Supplement after supplement, blood test after blood test, and no one could figure this out." Reed, who did not explain what actually helped treat her symptoms, also overhauled her diet. "I actually quit all caffeine about seven years ago, and my life got so much better as a result," Reed told Twilight costar Taylor Lautner and his wife, Tay Lautner, on their "Squeeze" podcast. "Life is a series of choices, [and] I also don't drink alcohol. How do I make my life feel the best it can be? What can I cut out that's not serving me anymore? Here we go, but, yeah, life got better without caffeine."