John Stamos never approved of his onscreen wife Lori Loughlin's IRL husband Mossimo Giannulli! In a candid new interview on the Good Guys podcast out on Monday, the Full House star shared his unconditional support for Lori, who is "devastated" going through a high profile separation from her longtime husband! The 62-year-old laid it out, saying: "40 years I've known her. You can see through people after a few years. This woman's a saint. I'm just heartbroken for her right now.