Rob Lowe's wife, Sheryl Lowe, is a straight-shooter when it comes to her husband. "You don't like me being on TikTok, do you?" Rob, 61, asked his wife during the Thursday, October 16, episode of his "Literally!" podcast. Sheryl, 64, confirmed that she is "absolutely not" a fan of her husband's TikTok habit. "I think it corrupts the brain," she stated. "Well, you know what? I want to be more specific. TikTok can be fun when used moderately, but for people that have addictions, it really does appeal to the compulsive part of those individuals.