Rosie O'Donnell is revealing why Keanu Reeves was "one of the worst" guests she had on her eponymous talk show. O'Donnell hosted over 1,000 episodes of The Rosie O'Donnell Show between 1996 and 2002 and interviewed a who's who of celebrities, including Tom Cruise, Julia Roberts and Britney Spears. During a Monday, October 13, appearance on Australian talk show Sam Pang Tonight, the comedian shared memories of some of her guests, including the Matrix star.