If we were to pick the most-anticipated show on Amazon Prime Video for 2025, it would be Fallout season 2. Unfortunately, that series won't be making its return until December 12. So we'll just have to find something else to name No. 1 for the fall. Now that the seasons have changed, Watch With Us has named its five most-anticipated Prime Video movies and shows of fall 2025. Some of our picks are arriving sooner than you may think, but you'll have to keep your eyes out for the others. 23 Must-Watch TV Shows on Amazon Prime Video Right Now (September 2025) 5.