When it comes to fighting illness, your friend group is critical. And for Clea Shearer, that crucial support during her breast cancer diagnosis in 2022 came from longtime pal Christina Applegate. "Christina has been my friend for a very, very long time," Shearer, cofounder of The Home Edit, tells Us Weekly. "I've known [her] forever, and she was my first phone call and the first person I thought of because she's been a long breast cancer advocate and has been dealing with this in the public eye for a very long time.