Jon Cryer and Charlie Sheen were costars on Two and a Half Men for eight seasons until Sheen was fired from the hit sitcom in 2011. "In the early years, the life with Charlie Sheen was great," Cryer told Entertainment Tonight in June 2022. Production for Two and a Half Men was halted twice, first in 2010 and then again in 2011, while the star attended rehab. Less than a week before Sheen was slated to return to the sitcom after his 2011 stint in rehab, he called into the Alex Jones radio show to rant about Lorre, calling him a "charlatan" and a "clown." The Platoon actor also mocked Alcoholics Anonymous, calling it "a bootleg cult" with "a 5 percent success rate." The following month, Sheen was fired from his top-rated series. Scroll through for a timeline of Cryer and Sheen's ups and downs: