Since Big Brother premiered in July 2000, viewers have been introduced to hundreds of houseguests, many of whom have become fan favorites and competed on the show multiple times. It all started with Eddie McGee, who became the first player to walk away with the $500,000 grand prize. Since then, the Julie Chen-hosted CBS reality competition has taken over televisions across the U.S. every summer - plus bonus seasons in 2008 and 2016 - and it has only become more popular as the years have gone by.