Christina Applegate got real about how her teen is coping with her health battle. In 2021, the actress revealed she was diagnosed with the chronic autoimmune disease multiple sclerosis, and she has been an open book about the difficulties of her illness since then. On Tuesday, Christina was brutally honest once again - this time about the impact MS has had on her 14-year-old daughter, Sadie LeNoble. Prepare to break out the tissues. It's a gut-wrenching update.