Christina Applegate says her MS battle has 'broken' her teenage daughter Christina Applegate admits her teenage daughter has lost the mother she once knew to MS. 28 August 2025 Christina Applegate says her battle with MS has "broken" her daughter Sadie. Christina Applegate says her daughter Sadie has struggled to see her mom's MS worsen The Dead to Me star was diagnosed with multiple sclerosis (MS) - a chronic autoimmune disease that affects the brain and central nervous system - in 2021, and she has detailed how her 14-year-old girl has struggled to see her mom lose control of her movement as...