Hulu went out of their way to transform Tell Me Lies' Grace Van Patten into Amanda Knox - but how does the show compare to Meredith Kercher's actual murder trial? The Twisted Tale of Amanda Knox, which premiered on August 20, is a limited series inspired by the story of how Knox "was wrongfully convicted for the tragic murder of her roommate, Meredith Kercher, and her 16-year odyssey to set herself free." In addition to Patten, the show also stars Sharon Horgan, John Hoogenakker, Francesco Acquaroli, Giuseppe De Domenico and Roberta Mattei.