To a certain segment of the population, John Stamos will always be Uncle Jesse. It's a role he played on Full House from 1987 to 1995, then reprised from 2016 to 2020 in Fuller House. He's fine with that, truly, but he also wants to challenge himself. "I just want to play a little more real," he tells Us. "I'm looking for my Breaking Bad." He may not have found his Walter White yet, but he's been flexing his acting muscles in a series of roles that are a far cry from the guitar-toting toddler wrangler we know and love.