TMDb/Grey's Anatomy TV Grey's Anatomy season 22 finale skipped the big cliffhangers. Showrunner Meg Marinis teases cast shakeups and surprises for season 23. May 9, 2026 AceShowbiz - Grey's Anatomy wrapped up its 22nd season without the usual dramatic cliffhangers, but showrunner Meg Marinis has hinted that season 23 may bring fresh surprises, including possible cast departures and story developments. In an interview with Deadline on May 7, Marinis stressed that fans will have to wait and see which characters return in the upcoming season.