Instagram/Anna Van Patten & Grace V TV Discover how sisters Grace and Anna Van Patten unite on screen for the first time in Hulu's The Twisted Tale of Amanda Knox. May 4, 2026 AceShowbiz - The limited series The Twisted Tale of Amanda Knox created a unique opportunity for sisters Grace Van Patten and Anna Van Patten to collaborate professionally. While Grace played the lead role as Amanda Knox, Anna portrayed Knox's sister, Deanna, marking their first on-screen appearance together.