Wikimedia Commons/The Boys Season 5 TV The Boys Season 5 adds Supernatural's Jared Padalecki & Misha Collins, joining Jensen Ackles in an epic reunion for the final season. April 28, 2026 AceShowbiz - The Boys fans are eagerly awaiting the arrival of Jared Padalecki in Season 5, and excitement has only grown after the recent reveal of his character. An earlier Instagram announcement teased that both Padalecki and Misha Collins, who previously worked with series creator Eric Kripke on Supernatural, will guest star in the final season of the Prime Video show, slated for release in 2025.