Searxng/Brilliant Minds NBC tv TV Brilliant Minds returns to NBC May 27 at 8 p.m. ET with final five episodes of season 2, starring Zachary Quinto as a neurologist with prosopagnosia. April 27, 2026 AceShowbiz - Brilliant Minds is set to return to NBC on Wednesday, May 27, at 8:00 p.m. ET, bringing back the remaining episodes of its second season after a lengthy hiatus. The medical drama stars Zachary Quinto as a neurologist with prosopagnosia, a condition that affects facial recognition, and is loosely inspired by the life and work of Oliver Sacks.