Selma Blair and Christina Applegate's connection remains strong even 25 years after The Sweetest Thing. Blair, 53, exclusively told Us the two have also bonded over their respective multiple sclerosis diagnoses over the last few years. "Right when she finished [Dead to Me], she was actually at my house, the kids were playing, and she was saying she wasn't well, and I was going, 'Oh, this reminds me a lot of me ... I couldn't walk, feet swelled up,'" Blair shared, recalling what she said when Applegate, 54, first broached her health issues.