Article continues below advertisementFans of Euphoria have seen a significant transformation of the cast since the show's debut in 2019.Based on the Israeli series of the same name, Euphoria follows troubled high school student Rue, played by Zendaya. Rue's struggle to stay sober after rehab serves as a central theme, alongside explorations of mental illness, toxic relationships and sexuality.The show's ensemble cast, which includes Hunter Schafer, Alexa Demie, Jacob Elordi, Sydney Sweeney, Maude Apatow and Colman Domingo, rapidly gained fame.