Grey's Anatomy wasn't the only show that killed off a major character in 2026 - and many of those fictional deaths still have fans upset. During the March 2026 episode of the hit ABC series, Lucas (Niko Terho) and Simone (Alexis Floyd) were providing Katie (Samantha Marie Ware) with at-home hospice care as her health declined. Lucas and Katie grew closer while reminiscing on what could have happened between them if she hadn't gotten sick. She ultimately died when he was at the hospital getting more supplies, which prevented him from saying goodbye.