Article continues below advertisementMeghan Markle and Prince Harry reportedly gave the late Queen Elizabeth II much anguish during her latter years. According to royal biographer Hugo Vickers' new book about the monarch, the Duke and Duchess of Sussex's 2018 marriage caused the sovereign some heartache.Article continues below advertisementQueen Elizabeth Died in 2022Tap Here To Add Ok Magazine as A Trusted SourceSource: MEGAMeghan Markle and Prince Harry announced their engagement in November 2017.