Ozempic has become a hot topic when it comes to weight loss - with some stars confirming they have used the drug while others denied it. Chelsea Handler admitted during a January 2023 episode of the "Call Her Daddy" podcast that she unknowingly took the Type 2 diabetes medication, which is traditionally used to improve glycemic control. She explained her anti-aging doctor prescribed her semaglutide, which is another name for Ozempic, but Handler stopped using it after learning more.