Article continues below advertisement2000Source: MEGAOprah Winfrey attended the Personal Growth Summit at the Shrine Auditorium in Los Angeles, Calif., on June 29, 2000. She inspired the audience by sharing tips on how to live the best life despite her struggles.In the years before the event, the talk show queen committed herself to a liquid diet and exercise. She lost 67 pounds in November 1988 but immediately regained the weight in 1990.