Share Tweet Pin Email By Isabella Torregiani 5:05pm PST, Mar 2, 2026 _ Christina Applegate, who was diagnosed with multiple sclerosis (MS) in 2021, recently admitted that, at one point, she was so unhappy with the way it affected her body, she "didn't look in the mirror for a year."Keep reading to find out how the disease changed the way she sees herself... MORE: Follow Wonderwall on MSN for more top news _ Christina Applegate recalled that she used to be a size zero and very thin - but even then, she never felt satisfied with her appearance.