Article continues below advertisementEric Dane's cause of death has officially been revealed.The Grey's Anatomy star died of respiratory failure, per his death certificate obtained by an outlet on Monday, March 2. The underlying cause of death was ALS.Dane announced his ALS diagnosis in April 2025, and his health deteriorated quickly in his final days.Article continues below advertisementSource: MEGAEric Dane died at age 53.Dane passed away on Thursday, February 19, at age 53. He left behind his estranged wife, Rebecca Gayheart, and kids Billie, 15, and Georgia, 13.