Share Tweet Pin Email By Isabella Torregiani 1:34pm PST, Feb 25, 2026 _ Since her 2021 multiple sclerosis (MS) diagnosis, Christina Applegate's life has been turned upside down. Now largely confined to her bed by chronic pain, the actress has opened up about how she's navigating her new reality.See how she's managing her new normal...MORE: Follow Wonderwall on MSN for more top news _ Despite the major changes brought on by her diagnosis, Christina Applegate still prioritizes helping her 15-year-old daughter, Sadie, shared with husband Martyn LeNoble, get to school and activities.