Eric Dane spoke candidly about how his ALS diagnosis made him feel in the months before his death at age 53. "I don't think this is the end of my story. I just don't feel like in my heart this is the end for me," Dane shared in a June 2025 interview with ABC News. "I'm fighting as much as I can. There's so much about it that's out of my control." While the Grey's Anatomy and Euphoria actor tried to stay positive, the diagnosis - which impacts 5,000 new people every year - made him feel angry at times.