Amyotrophic lateral sclerosis is more commonly known as ALS, or Lou Gehrig's disease. Grey's Anatomy alum Eric Dane announced in April 2025 that he had been diagnosed with the nervous system disease. "I have been diagnosed with ALS," the actor shared in a statement. "I am grateful to have my loving family by my side as we navigate this next chapter." The actor was married to wife Rebecca Gayheart, with whom he shared two daughters.