Details about the health of Savannah Guthrie's mom, Nancy Guthrie, have been revealed following her disappearance. Nancy, 84, was first reported missing in Arizona on February 1. She was last seen on January 31 after having dinner with daughter Annie Guthrie and son-in-law Tommaso Cioni, who allegedly dropped her off at home after the meal. Law enforcement officials believe that Nancy was taken from her house in the middle of the night. Pima County Sheriff Chris Nanos told Us Weekly exclusively that "something unusual occurred" in Nancy's home. "We don't want anybody to lose hope. But in the same sense, just as there's hope, there's also things that point to us that say, 'This lady's in danger,'" he added. "It does have to do with what was described to us about the scene. I've been doing this for 50 years. When something doesn't sit well, it doesn't sit well." Savannah Guthrie and mother Nancy Guthrie. Nathan Congleton/NBC via Getty Images As the investigation into Nancy's disappearance continues, Savannah - who has been absent from the Today show since her mom went missing -and her siblings, Annie and Camron, have released several videos begging the apparent kidnappers for the safe return to Nancy. "We received your message and we understand. We beg you now to return our mother to us so that we can celebrate with her," Savannah said in a video released on February 7. "This is the only way we will have peace. This is very valuable to us and we will pay." There have been several reports that Savannah and her family received a ransom note that demanded $6 million in Bitcoin in exchange for Nancy. Savannah addressed the situation in a solo video published via social media on February 9. "She was taken, and we don't know where, and we need your help," Savannah told her followers. "So, I'm coming on just to ask you, not just for your prayers, but no matter where you are, even if you're far from Tucson, if you see anything, you hear anything, if there's anything at all that seems strange to you, that you report to law enforcement." Savannah Guthrie's Sister Was Last Person to See Mom Before Her Disappearance Throughout Nancy's case, there has been a major emphasis on concerns surrounding her well-being and the medication she's taking. Keep scrolling for everything that's been revealed about Nancy Guthrie's health so far: What Did Pima County Sheriff Chris Nanos Say About Nancy Guthrie's Health? Nancy was initially referred to as a "vulnerable adult" after it was reported that she went missing. However, it has since been clarified that she has "no cognitive issues at all." Nanos offered more insight into Nancy's well-being, explaining during a February 2 press conference that she was "not in good" physical health. "She's very alert, she's of good, sound mind," he added. "I hope we find her safe and sound, but we can't ignore what's in front of us." What Did Jenna Bush Hager Say About Nancy Guthrie's Medication? Bush Hager told Today viewers during the show's February 2 broadcast that she knew Nancy "personally." She noted that Nancy "takes daily medication" that she needs "for survival." Bush Hager also speculated that Nancy was "without her medication" when she went missing. What Did the 911 Call Reveal About Nancy Guthrie's Health? Nancy has "high blood pressure, [a] pacemaker and cardiac issues," according to the 911 call obtained by Fox News Digital on February 3. What Did Savannah Guthrie Say About Mom Nancy's Health? Savannah sat with her siblings in a video released on February 4. The NBC anchor called Nancy her family's "heart and home," noting that her mother's health and heart are "fragile." Savannah said her mom lives in "constant pain" and needs "medicine to survive."