Catherine O'Hara had many memorable roles throughout her extensive acting career. O'Hara got her start in 1975, making an appearance on the comedy show Wayne and Shuster. One year later, she had a breakthrough role on the Canadian sketch comedy show Second City Television, which won her an Emmy. In 1980, O'Hara made her film debut in the rom-com Nothing Personal. The actress grew more popular following her roles in After Hours, Heartburn and Beetlejuice. However, in 1990, she scored one of her most iconic roles, playing Kate McCallister in Home Alone alongside Macaulay Culkin.